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Investigation of Anti-Hyperlipidemic Activity of Vinpocetine in Wistar Rat
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| Author:
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ANUBHAV DUBEY, MAMTA TIWARI, VIKAS KUMAR, KSHAMA SRIVASTAVA, AKANKSHA SINGH
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| Abstract:
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The current research is designed to explore the effect of Vinpocetine on lipid profiles in Dexamethasone induced hyperlipidemia in Wistar rodents. The rodents were completely randomized into five groups comprising 6 rodents each. The groups were treated as follows: Groups II, III, IV, and V were administered a subcutaneous injection of Dexamethasone (10 mg-kg/day S.C) for 8 days to produce hyperlipidemia. The rodents in normal and hyperlipidemia control groups were taken normal saline while Group III animals have taken Gemfibrozil (10 mg/kg/day I.P. suspended in gum acacia in water. Group IV and V rodents have taken Vinpocetine by oral route in doses of 30 and 60 mg/kg/day, separately, throughout the 8 days experiments.
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| Keyword:
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Vinpocetine, Dexamethasone, Hyperlipidemia, Lipid-profile, Gemfibrozil.
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2020.12.02.250
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| Download:
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Request For Article
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