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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Formation, Characterization, Basic Studies and Biological Effect of Mixed Ligand Complexes of Cu-ion and Ni-ion Derived from Azo Compounds, Schiff bases and (1,10, phen)

Author: LAYLA. MOHAMMED, MUNA ABASS HADI, MITHAQ SAEED MOHAMMED
Abstract: New Mixed ligand complexes of Cu (II)then Ni (II) with L1 (1-benzyl 2,3-dialkyl -4-4'chloro Salicylaldene) pyra-zole-5-one),(L2) 2- [ (2-Benzothiazolyl) -4-methoxy phenol ],(L3) 1,5-dimethyl-4-((4-methyl-1H-imidazol-2-yl)diazenyl)-2-benzyl-1,2-dihydro-3H-pyrazol-3-one and L5 (1,10,phen) have been synthesized These ion chelates complexes have been brandedwithprimarystudy,IR,1H-NMR,UV-Vis, Molar conductivities, Attractive moments, Spectral data exhibited the(L1,L2) actions as mono anionic tridentate ligand coordinating to the metal ion through(O,N,O),(N,N,O)donor atoms, imine ligand (L4) as monoanionic bidentate coordinating through(O,N)donor atoms,(L3)acts as impartial tridentate ligand coordinating to the metal ion through(N,N,O)and (1,10,phen) acts as neutral didentate ligand coordination from through (N, N).Cu(II) and Ni(II) complexes perform to have an octahedral geometry. Bio-effect studies of the ligand besides to its metal complexes alongside numerous bacteria s.aureus, Escherichia coli, klebsiella pneumonia, Aspergillus.n, Aspergillus. f, Rhizoctoniabataicola and Trichoderma, are stated. Compounds gave the high result of bustle.
Keyword: Characterization, New Ligand, Complexes, Octahedral, Biological Activity, Ligand.
DOI: https://doi.org/10.31838/ijpr/2020.12.01.238
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