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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Synthesis, Characterization, Theoretical Study and Biological Activity of Schiff base Metal Complexes Derived from Cefotaxime with 5, 5-diethyl-6-iminodihydropyrim idine-2, 4(1H, 3H)-Dione

Author: SAHAR HASSAN, ZAHRAA N. ABD, NAFEESA J. KADHIM, NIDHAL M. HASSAN
Abstract: Synthesis of Complexes for Co (II), Ni (II) , Cu (II) and Zn (II) with New ligand Schiff base derivative from cefotaxime and barbiton has been characterized and prepared through Atomic Absorption-Spectrophotometer (AAS), electronic and infrared spectra , molar conductivity measurements in addition to magnetic moment measurements . It is obvious to see the ligands act as a neutral bidentate and ligands forming chalets with 1:1 (metal: ligand), octahedral construction is proposed for (Ni, Cu and Zn) metal complexes and tetrahedral for Co based on to the analytical result and then studying the biological activity.
Keyword: Synthesis, Characterization, Theoretical Study.
DOI: https://doi.org/10.31838/ijpr/2020.12.04.129
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