IJPR  articles are Indexed in SCOPUSClick Here     Impact Factor for Five Years is 0.13 (2013 - 2018).    

logo

INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence

IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
Current Issue
No Data found.
Article In Press
Life review of elderly depression
Development and application of ATR-FTIR spectroscopy for mixture homogeneity in pharmaceutical application
The Increasing Damage in Tubular Cell of Infant Mice’s Kidneys from Carbofuran Exposure during its Mothers’ Lactation Period
Trend of transsexualism problem and its implications towards muslim community in Malaysia
Development and validation of RP-HPLC method for the estimation of pidotimod in tablet dosage form
Evaluation of neurotoxicity of the ethanolic bark extract of Holarrhena pubescens Wall. ex G.Don in mice
Design, synthesis and evaluation of 2-aminobenzimidazole derivatives: strong candidate for PPAR gamma agonists.
Prediction of Heart Disease Using Feature Selection and Random Forest Ensemble Method
Strategies for Antiviral Drugs from Plants by Targeting the Hemagglutinin, Neuraminidase and other receptors of Influenza A virus
The impact of human resource and quality management in health care: A Review
12345678910...
ADOBE READER

(Require Adobe Acrobat Reader to open, If you don't have Adobe Acrobat Reader)

Index Page 1
Click here to Download
IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

Click to download
 

Article Detail

Label
Label
Expression of tissue-specific genes in mice with hepatocarcinogenesis

Author: NIZOM ERMATOV, GULMIRA KASSYMOVA, GULMIRA KASSYMOVA, KHOSIYAT TAJIYEVA, MUKHARRAMA KHASANOVA, MAVJUDA ALIMUKHAMEDOVA, SEVARA AZIMOVA
Abstract: Hepatocarcinogenesis is a multi-stage process associated with a change in the spectrum of the genes expressed by the cell. The scheme of molecular mechanisms leading to malignancy of hepatocyte is still not fully characterized. Objective: To study the general patterns of gene expression dysfunction during the progression of hepatocellular carcinomas. To this end, we studied the results of studies of 28 mice that were induced by a single injection of diethylnitrosamine. As a result of the data obtained, the relationship between specific transcriptional regulators and the level of tumor differentiation is shown. Based on the study, it can be assumed that analysis of changes in the expression levels of tissue-specific genes in clinical samples will allow us to answer the question of the validity of the revealed patterns for human hepatocarcinogenesis.
Keyword: hepatocarcinoma, tissue-specific genes, expression, types of hepatocarcinomas, histological structure.
DOI: https://doi.org/10.31838/ijpr/2020.12.03.245
Download: Request For Article
 












ONLINE SUBMISSION
USER LOGIN


Username
Password
Login | Register
News & Events
SCImago Journal & Country Rank

Terms and Conditions
Disclaimer
Refund Policy
Instrucations for Subscribers
Privacy Policy

Copyrights Form

0.12
2018CiteScore
 
8th percentile
Powered by  Scopus
Google Scholar

hit counters free