Features of the immune system in primary headache in children and adolescents.
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Author:
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DURDONA ALIDJANOVA, YAKUTKHON MADJIDOVA, SAYDOLIM USMANOV, DILFUZA NOSIROVA, MUKHLISA NURMUKHAMEDOVA
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Abstract:
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The article contains an analysis of our own clinical studies that study the neurological and immunological
aspects of headache (HA) in children. Were examined 24 children with simple migraine, 18 children with
migraine with aura and 13 children with tension headache, with determining the number of circulating Tlymphocytes
(CD3+) and their main immune regulating subpopulations of T-helper and T-cytotoxic cells
(CD4+, CD8+), B lymphocytes (CD20+), immune regulatory index (IRI), marker of apoptosis (CD95+) in the
inter attack period, with remission of somatic diseases.
As a result of a comparative analysis of the obtained indicators of the immune system in patients, there was no
significant deviation in the cellular immunity parameters relative to control values, which indicates that they
have immune homeostasis in the inter attack period.
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Keyword:
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headache immunology, age of child, primary headaches, migraine in children, tension headache, cellular immunity, inter attack period.
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EOI:
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DOI:
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https://doi.org/10.31838/ijpr/2020.12.03.239
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