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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Features of the immune system in primary headache in children and adolescents.

Author: DURDONA ALIDJANOVA, YAKUTKHON MADJIDOVA, SAYDOLIM USMANOV, DILFUZA NOSIROVA, MUKHLISA NURMUKHAMEDOVA
Abstract: The article contains an analysis of our own clinical studies that study the neurological and immunological aspects of headache (HA) in children. Were examined 24 children with simple migraine, 18 children with migraine with aura and 13 children with tension headache, with determining the number of circulating Tlymphocytes (CD3+) and their main immune regulating subpopulations of T-helper and T-cytotoxic cells (CD4+, CD8+), B lymphocytes (CD20+), immune regulatory index (IRI), marker of apoptosis (CD95+) in the inter attack period, with remission of somatic diseases. As a result of a comparative analysis of the obtained indicators of the immune system in patients, there was no significant deviation in the cellular immunity parameters relative to control values, which indicates that they have immune homeostasis in the inter attack period.
Keyword: headache immunology, age of child, primary headaches, migraine in children, tension headache, cellular immunity, inter attack period.
DOI: https://doi.org/10.31838/ijpr/2020.12.03.239
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0.12
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