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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Chemotherapy tolerance in children with tuberculosis

Author: FATIMA TASHPULATOVA, MAHLIYO ABDUSALOMOVA
Abstract: In order to study the tolerability of chemotherapy for tuberculosis in children, 101 patients aged 1-17 years were examined. It was found that in the dynamics of 41.5 ± 4.8% of children, the development of adverse reactions to chemotherapy was noted. The most frequently encountered gastrointestinal tract syndromes (28.5 ± 6.9%) and liver (23.8 ± 6.5%). Adverse reactions, mainly in 47.6 ± 7.7% of sick children, were moderately expressed. Clinical manifestations of AR correlated with changes in biochemical parameters. In 92.8 ± 3.9% of sick children with tuberculosis, adverse reactions from anti-TB drugs were eliminated. The need for the prevention of adverse reactions from chemotherapy in children with tuberculosis is justified.
Keyword: tuberculosis, children with tuberculosis, anti-TB drugs, adverse reactions.
DOI: https://doi.org/10.31838/ijpr/2020.12.04.108
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