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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Specific course of the clinical and neurovisual features of the cerebral stroke caused by reversible cerebral vasoconstriction syndrome

Author: ELYOR TASHKENOV, GULNORA RAKHIMB?EVA, DILFUSA ABDUK?DIROVA
Abstract: To study the specific course of the clinical and neurovisual features of the cerebral stroke caused by reversible cerebral vasoconstriction syndrome (RCVS). 30 patients were under our control. The control group consisted of 19 women and 11 men. The age of patients is from 15 to 60 years (the average age (43.3 ± 0.7)). We performed MRI and MR angiographic studies of the brain using the apparatus for MRI “TOSHIBA” (1.5T), conducted USDS of the cerebral vessels, and used the MMSE short mental health assessment scale for an overall assessment of the cognitive system. We used the Reisberg scale (2008) to assess the decrease in overall cognitive activity with an emphasis on memory, the VAS scale to assess the intensity of headaches and the results were statistically processed. Result: the diagnosis of RCVS (Fleming-Call syndrome) is made on the basis of the patient’s clinical picture, the nature of the headache (development speed, headache intensity (100%), nausea (90%)), on the basis of vasoconstriction changes in the brain vessels in an MRI study T1, T2, FLAIR and in blood vessel research modes. In the first group (n = 23), there were no focal signs in the brain in the T1, T2, and FLAIR modes; vasoconstriction changes in the cerebral vessels were detected in the MR angiographic. In the second group (n = 7), focal changes in the brain were detected in the T1, T2, and FLAIR modes, as well as vasoconstriction changes in the cerebral vessels in the MR angiographic. USDS examination revealed atherosclerotic changes in cerebral vessels in 42% of patients: grade I or II stenosis, and in 58% of patients atherosclerotic changes in cerebral vessels were not detected. Conclusions: 1. It has been established that most cases of cerebral stroke caused by RCVS (Fleming-Call syndrome) occur in patients under the age of 55 and are accompanied by high-intensity headaches and vasoconstrictive changes in cerebral vessels.
Keyword: Reversible cerebral vasoconstriction syndrome, Fleming-Call syndrome, MR angiography, ultrasound dopplerography.
DOI: https://doi.org/10.31838/ijpr/2020.12.04.098
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