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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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The level of biogenic amines and activity of cholinesterase’s in patients with uterine myoma

Author: NILUFAR AKHMEDOVA, SHOISTA GOZIYEVA, MAKHLIYO MAMADIYEVA, SHOHIDA SATIMOVA, GULRUH QUZIYEVA
Abstract: Non-operative treatment of patients with uterine myoma is still an actual problem of modern gynecology. In order to treat a variety of gynecological diseases in combination with somatic, nowadays many researchers recommend assigning new class of agents - statins. The aim of the study was to investigate the influence of Simvastatin on the level of histamine, serotonin, and cholinesterase in the blood of women with uterine myoma. The investigation showed that the clinical efficacy of Simvastatin in the treatment of women with uterine myoma caused by a decline in blood levels of histamine, serotonin, and cholinesterase, which are known to be involved in the mechanisms of generation of proinflammatory regain.
Keyword: uterine myoma, statins, simvastatin, biogenic amines, dyslipidemia.
DOI: https://doi.org/10.31838/ijpr/2020.12.04.094
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