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Effect of heparinised irrigating solution during cataract surgery on postoperative inflammation.
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| Author:
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ABHISHEK GU, SACHIN DAIGAVANE, PRASANNA MUKUND PALSODKAR
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| Abstract:
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Background: Intra ocular surgery is an ocular trauma. Inflammation following cataract surgery is because of break in blood aqueous barrier along with prostaglandin production causing discomfort, pain and can lead to complications like posterior synechiae and cystoid macular edema. Using heparinised infusion during cataract surgery is known to reduce post-operative inflammation.
Trial design: This is a randomised control trial that will be conducted department of Ophthalmology, AVBRH. Methods: Total of 330 subjects will be included in the study. Among them 165 will receive heparinised irrigating solution and 165 will receive non heparinised irrigating solution during cataract surgery. Post-operative anterior chamber cells, flare and iris pigment dispersion will be evaluated at intervals of post-op day 1, at end of 2 weeks and at end of 8 weeks.
Results: We expect that post-operative inflammation will be significantly less in patients in whom heparinised irrigating fluid has been used intra operatively. Hence these patients will have better visual outcome and lesser postoperative complications.
Conclusion: Inclusion of heparin in irrigating fluid is a simple yet effective method to reduce post-operative inflammation and hence reduce chances of complications and have better visual outcome.
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| Keyword:
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Cataract, Phacoemulsification, Heparin, Post-operative inflammation, anterior chamber cells, anterior chamber flare, iris pigment dispersion.
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2019.11.02.200
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| Download:
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Request For Article
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