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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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A study of central corneal thickness and corneal endothelial cell changes in type 2 diabetes mellitus with and without diabetic retinopathy: a case control study.

Author: DR. RAMANI, DR. SHASHANK BANAIT, MAHESH PAWAR
Abstract: Background-. It is essential to evaluate the amount of endothelial cell damage in diabetes patient and diabetic retinopathy patients. Objectives- Relate thickness of central cornea in type 2 diabetes mellitus patient without diabetic retinopathy with same sex and same age matched normal person .To associate (CCT) of type 2 DM patient with diabetic retinopathy with period in addition to gender matched normal person.Compare corneal endothelial variations in patient with diabetes mellitus without diabetic retinopathy age/sex matched normal person.To compare corneal endothelial changes in patient with diabetes mellitus with diabetic retinopathy with age/sex matched normal person.To link the endothelial cell density (ECD) and percentage polymegathism in addition to pleomorphism in patient with diabetes mellitus without diabetic retinopathy with age/sex matched individual. To compare the endothelial cell thickness and percentage polymegathism and pleomorphism in patient with diabetes mellitus with diabetic retinopathy Results The central corneal thickness is likely to be more in type 2 diabetes patients than non-diabetic individual. The endothelial cell changes are more in type 2 diabetes patient than non – diabetic individual.
Keyword: Specular Microscopy, Endothelial Cell Count, Diabetes, Diabetic retinopathy, central corneal thickness, corneal endothelial cell
DOI: https://doi.org/10.31838/ijpr/2019.11.01.220
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