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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Study of metabolic syndrome in patients of acne vulgaris

Author: DR. CHANDAK, DR. ADARSHLATA SINGH, DR. AMOLI BELSARE
Abstract: Background/rationale: Acne vulgaris is an unremitting chronic inflammatory disease of the pilosebaceous units. It is considered as amongst the most prevalent skin disorders across the globe especially affecting the individuals of adolescent age group and young adults. Metabolic syndrome (MetS) is a complex systemic disorder that makes the individuals susceptible to development of type 2 diabetes mellitus (T2DM) and cardio-vascular diseases. Any dysregulation of skin physiological homeostasis can predispose to MetS and vice versa. Hence, parameters for MetS need to be evaluated in patients of acne vulgaris patients. Objectives: 1. To study clinical features of acne vulgaris. 2.To study the waist circumference, High Density Lipoprotein (HDL) levels, Triglyceride (TG) levels, blood pressure, fasting glucose in patients of acne vulgaris and controls. 3.To study the correlation between the above parameters and acne vulgaris. 4.To study the correlation between severity of acne vulgaris and metabolic syndrome. Methods: It is a prospective, case control study and will be carried out in the “Department of Dermatology, Venereology and Leprosy, JNMC and AVBRH, Sawangi, Wardha”. A total of 65 patients above the age of 18 years, irrespective of gender, suffering from any grade of acne will be included in the study along with 65 controls after taking their informed consent. After considering the inclusion and exclusion criteria, the following parameters will be studied – waist circumference, blood pressure, fasting blood glucose, high density lipid (HDL) levels and triglyceride levels (TG) levels and a correlation between acne and metabolic syndrome will be established. Results: The result would be undertaken in SPSS software. Conclusion: The conclusion will be based on findings for study protocol.
Keyword: Acne, Metabolic Syndrome, fasting lipid profile, blood pressure, waist circumference, blood pressure
DOI: https://doi.org/10.31838/ijpr/2019.11.01.216
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