Correlation of total serum LDH levels with differentiation of breast carcinoma
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Author:
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DR. HARSHALA, DR. HIWALE KESHAO, DR. VAGHA SUNITA, CHETAN SUDHAKARRAO GODE
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Abstract:
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Background- Breast carcinoma being one of the most common carcinomas and the leading sourec of death worldwide is studied variedly for a better prognosis. Serum LDH, a metabolic enzyme, helps in the fulfillment metabolic requirements of these malignant cells. Thus aggressiveness of tumour growth directly correlates with serum LDH levels and acts as a diagnostic and prognostic marker in breast carcinoma patients The study aims to correlation of serum LDH levels with differentiation of carcinoma breast.
Objective: To evaluate and estimate total serum LDH required in the diagnosis of breast carcinoma patients and to correlate the total serum LDH levels to the differentiation of breast carcinoma.
Method: 80 cases wil be studied. Statistical analysis will be concluded by using chi-square test, student unpaired t-test and SPSS 24 version and Graphical Prism 7.0 version software will be used in the analysis and the level of significance considered will be p<0.05.
Conclusion: Depending upon the observations and results obtained from the cases and control group, the conclusion will be drawn.
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Keyword:
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Breast Carcinoma, Serum LDH, Bloom-Richardson (Nottingham) Combined Scores.
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EOI:
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-
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DOI:
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https://doi.org/10.31838/ijpr/2019.11.01.214
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