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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Correlation of total serum LDH levels with differentiation of breast carcinoma

Author: DR. HARSHALA, DR. HIWALE KESHAO, DR. VAGHA SUNITA, CHETAN SUDHAKARRAO GODE
Abstract: Background- Breast carcinoma being one of the most common carcinomas and the leading sourec of death worldwide is studied variedly for a better prognosis. Serum LDH, a metabolic enzyme, helps in the fulfillment metabolic requirements of these malignant cells. Thus aggressiveness of tumour growth directly correlates with serum LDH levels and acts as a diagnostic and prognostic marker in breast carcinoma patients The study aims to correlation of serum LDH levels with differentiation of carcinoma breast. Objective: To evaluate and estimate total serum LDH required in the diagnosis of breast carcinoma patients and to correlate the total serum LDH levels to the differentiation of breast carcinoma. Method: 80 cases wil be studied. Statistical analysis will be concluded by using chi-square test, student unpaired t-test and SPSS 24 version and Graphical Prism 7.0 version software will be used in the analysis and the level of significance considered will be p<0.05. Conclusion: Depending upon the observations and results obtained from the cases and control group, the conclusion will be drawn.
Keyword: Breast Carcinoma, Serum LDH, Bloom-Richardson (Nottingham) Combined Scores.
DOI: https://doi.org/10.31838/ijpr/2019.11.01.214
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