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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Assessment of renal function in obese individuals

Author: DR. R., DR. SAMARTH SHUKLA, DR. SOURYA ACHARYA, DR. SUNITA VAGHA, DR. PRACHI PALSODKAR
Abstract: Background/rationale: Obesity is most common form of malnutrition. Amongst chronic and non-communicable diseases (hypertension, type II diabetes, hyperlipidemia), CKD, nephrolithiasis, malignancies etc, it’s an important risk factor. The burden of chronic kidney disease is piling up rapidly that it can lead to End Stage Renal Disease and increased cardiovascular morbidity and mortality. Thus, the renal function needs to be evaluated amongst obese individuals. Objectives: 1. To identify obese individuals based on WHO Asian Pacific guidelines and categorize them as Metabolically Healthy Obese and Metabolically Unhealthy Obese. 2.To compare renal parameters like serum creatinine, Blood urea nitrogen, eGFR, microalbuminuria in obese and normal individuals and between MHO and MUO. Methods: It is Cross sectional, Analytical study and will be conducted in the Department of Pathology, J.N.M.C and AVBRH, Sawangi (Meghe), Wardha. A total of 300 individuals will be studied and prior informed consent will be taken. After considering the inclusion - exclusion criteria, we will identify obese individuals with the following parameters – BMI, waist hip ratio, Waist circumference based on WHO Asian Pacific guidelines and classify them as MHO and MUO. Evaluation of the renal parameters like serum concentrations of creatinine, BUN, eGFR and microalbuminuria by Virtos integrated system – ortho diagnostics will be done at Department of Pathology , J.N.M.C.Comparison of the anthropometric parameters with the renal parameters in the obese and normal individuals will be done and a correlation between renal parameters of MHO, MUO and Normal individuals will be established. Expected Results: The renal parameters are expected to be useful in normal and obese cases. Conclusion: The conclusion will be based on findings for study of protocol.
Keyword: MHO,MUO
DOI: https://doi.org/10.31838/ijpr/2019.11.01.209
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