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Relation of Stromal Collagen with Mast Cells in Different Grades of OSCC
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| Author:
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BELGAUMI U.I, VIBHUTE N, KADASHETTI V, SUSHMA BOMMANAVAR, KAMATE W, TEWARY S, PAWASHE K
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| Abstract:
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Cancer is a disease involving interactions between cancer cells and stromal cells. Mast cells and collagen in oral squamous cell carcinoma (OSCC) has been studied individually here. It is not known if mast cells influence collagen in the microenvironment of OSCC, which in turn may influence tumour progression. The data was tabulated and analyzed using Pearson correlation coefficient. It was observed that mast cell count decreased with increasing grade of OSCC. Collagen in Well differentiated OSCC showed a predominant red orange hue, in moderately differentiated OSCC showed a yellow orange hue and in poorly differentiated OSCC showed a greenish yellow hue. The present research concluded that a co-relation exists between the grade of OSCC, mast cells and type of collagen.
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| Keyword:
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Tumor Grading, Mast cells, collagen, picrosirius red, toluidine blue
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2020.12.03.227
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| Download:
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Request For Article
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