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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Comparative Study of Sevoflurane with Halothane for Anaesthesia in a Clinical Setting

Author: DR. B,
Abstract: The new inhalation anesthetic agent sevoflurane introduced recently in the clinical practice, having lower blood gas solubility allow for rapid induction, has less myocardial depressant effects may make it a suitable agent for induction as well as maintenance of anaesthesia. Hence, the current research was conducted to compare intubation, induction, haemodynamic and emergence characteristics of halothane and sevoflurane. This comparative clinical study was carried out at Krishna Institute of Medical Sciences and Hospital, Karad. From the present study it is seen that, Halothane in the concentration of 0.5-5% produces induction in 137.8 secs (SD 33.3secs) and sevoflurane in the concentration of 1-7% produces induction in 70.95 secs (SD 14.6secs). Thus sevoflurane produces significantly rapid induction compared to halothane (p<0.05).
Keyword: sevoflurane, halothane, intubation, nitrous oxide
DOI: https://doi.org/10.31838/ijpr/2020.12.02.199
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