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Visible Spectrophotometric Method for Estimation of inezolid in Tablet and Injection Dosage Form
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| Author:
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UPLOADED BY-ADMIN, SATISH A. PATEL
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| Abstract:
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A simple, sensitive, accurate, precise, economical and rapid visible spectrophotometric method has been developed for
the estimation of linezolid in tablets. The method is based on the reaction of linezolid with Folin-Ciocalteu reagent in
presence of 20% sodium carbonate solution, giving blue colour chromogen, which shows maximum absorbance at 765 nm
against reagent blank. The chromogen obeyed Beer’s law in the concentration range of 10-100 µg/ml for linezolid. The
results of the analysis have been validated statistically and by recovery studies.
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| Keyword:
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Linezolid, Chromogen, Folin-Ciocalteu reagent, Sodium carbonate, Visible spectrophotometric, Tablet
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| EOI:
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| DOI:
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| Download:
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