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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Comparative Evaluation of Reparative Dentin Formation by Using Different Pulp Capping Agents: An In Vivo Study

Author: SNEHA MALI, SALEEM MAKANDAR, T.M. MANGALA, ABHIJEET PHASE
Abstract: Aim: The study carried objective to compare and evaluate the efficiency of Ca(OH)2, MTA on pulp repair. Materials and method: 20 Dental patients between age group of 18yrs-26yrs which were scheduled for premolars extraction for orthodontic explanation were selected. After Local anesthesia and complete isolation with elastic dam. Preparation of the ideal class I cavity by using sterile straight carbide bur (0.8mm) was done. an exposure of approximately 1.2 mm in diameter was done at center of the pulpal floor with round carbide bur of diameter of 1.2 mm was done Group I Exposed pulp of the teeth was capped with 2 mm of thick layer Ca(OH)2 ,Group II Exposed pulp of the teeth was capped with 2 mm thick layer of WMTA.. After 30 seconds Glass ionomer (GC Fuji II, Japan) restoration was done. Atraumatic extraction was conducted after 8 weeks. Specimens were prepared for histological analysis and evaluated beneath light microscope at 4x and 400x magnification for inflammatory cell response, Tissue disorganization, Hard tissue formation. Descriptive statistics and inferential statistics were done using Tukey’s HSD pair wise comparison test and one way ANOVA test. Results: Significance difference was seen in intensity and extensity of inflammatory cells; tissue disorganization and hard tissue formation among two groups (0.00<0.005).except for formation of dental bridge in continuity. Conclusion: Mineral Trioxide Aggregate is appropriate, biocompatible materials for pulp capping had optimum efficacy in the clinical setting but histological analysis directed favorable therapeutic effects of MTA than calcium hydroxide in teeth.
Keyword: Calcium hydroxide, MTA, Pulp capping agent, Reparative Dentin
DOI: https://doi.org/10.31838/ijpr/2020.12.04.041
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