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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Hydrogel Systems: Their Classification, Preparation and Biomedical Applications

Author: SUMALATDA BALAMURUGAN, MANISHA MURALI, ARAVINDHANATHAN VENKATESAN, NAGASAMY VENKATESH D
Abstract: Hydrogels are three-dimensional networks cross linked with polymer chain, insoluble hydrophilic nature, that are capable of absorbing large quantities of biological fluids or water, greater than their dry weight. Thus the hydrogels have an intrinsic potential to be utilized as vital candidates for drug delivery vectors, biosensors and biomaterials, and matrices, carriers and scaffolds for tissue engineering. According to the specific application of hydrogels, hydrogels of various properties with flexible manner has been designed to serve the purpose. Scientist and researchers utilize various scientific techniques to design hydrogels with potential properties overcoming the pitfalls of conventional hydrogels. In this critical review, various class of hydrogels are briefly discussed with their examples from literature reports. Hydrogels are sensitive to various stimuli including pH, heating, light, temperature, and chemicals, which depends on their chemical composition. This review addresses the hydrogels prepared from natural materials such as polypeptides and polysaccharides, as well as various types of synthetic hydrogels from the recent literature. Synthesis and Characterisation of hydrogels have also been discussed in a brief manner. In conclusion, application of hydrogels in different disciplinaries like self-healing, cell culture, drug delivery and cancer treatments have also been discussed.
Keyword: Hydrogel, Natural polymers, synthetic polymers, Hydrogel synthesis, Biomedical application.
DOI: https://doi.org/10.31838/ijpr/2020.12.04.036
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