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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Strategies for Antiviral Drugs from Plants by Targeting the Hemagglutinin, Neuraminidase and other receptors of Influenza A virus

Author: SONU BANSAL, G. SIBI
Abstract: Influenza A virus (IAV) is a serious threat to public health and socioeconomic impacts. Targeting the viral surface protein that mediates viral binding and entry could be an effective way of controlling viral infection. However, the appearance of resistant strains necessitates a constant search for new drugs and the natural products from traditional medicinal plants continue to serve as a source of new anti-influenza drug leads. In this article, we investigated the potential candidates that target hemagglutinin, neuraminidase and other receptors of influenza A virus from plant origin. Based on the review, there are plants which inhibit the virus in more than one way indicating their anti-influenza activity.
Keyword: Influenza A virus, hemagglutinin, neuraminidase, the NF-kB pathway, antiviral.
DOI: https://doi.org/10.31838/ijpr/2020.12.04.014
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0.12
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