IJPR  articles are Indexed in SCOPUSClick Here     Impact Factor for Five Years is 0.13 (2013 - 2018).    

logo

INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence

IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
Current Issue
No Data found.
Article In Press
Life review of elderly depression
Development and application of ATR-FTIR spectroscopy for mixture homogeneity in pharmaceutical application
The Increasing Damage in Tubular Cell of Infant Mice’s Kidneys from Carbofuran Exposure during its Mothers’ Lactation Period
Trend of transsexualism problem and its implications towards muslim community in Malaysia
Development and validation of RP-HPLC method for the estimation of pidotimod in tablet dosage form
Evaluation of neurotoxicity of the ethanolic bark extract of Holarrhena pubescens Wall. ex G.Don in mice
Design, synthesis and evaluation of 2-aminobenzimidazole derivatives: strong candidate for PPAR gamma agonists.
Prediction of Heart Disease Using Feature Selection and Random Forest Ensemble Method
Strategies for Antiviral Drugs from Plants by Targeting the Hemagglutinin, Neuraminidase and other receptors of Influenza A virus
The impact of human resource and quality management in health care: A Review
12345678910...
ADOBE READER

(Require Adobe Acrobat Reader to open, If you don't have Adobe Acrobat Reader)

Index Page 1
Click here to Download
IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

Click to download
 

Article Detail

Label
Label
Evaluation of Pharmacological Activities of Itchy Leaf Extracts (Laportea decumana (Roxb.) Wedd.)

Author: EVA SIMAREMARE, ELSYE GUNAWAN, YULIANA RUTH YABANSABRA
Abstract: Itchy leaves [Laportea decumana (Roxb.) Wedd.] have been used as traditional medicine by Papuans as painkillers, for treating stiffness or aches, headaches, stomach aches, sore muscles, joints, and bruises. This study was conducted to evaluate the analgesic, anti-inflammatory, antibacterial, and antidiabetic activities of ethanol extract, ethyl acetate, and n-hexane leaves of L. decumana. In this research analgesic tests were carried out by the tail flick method, anti-inflammatory test: paw edema method, the antibacterial testing: disk method, and the anticoagulant test: Lee and White methods and the blood smear method. The results of the study of analgesic activity showed that there were significant differences in the treatment of ethanol, ethyl acetate, and N-hexane extract (sig < 0.05) dose of 200 mg/Kg BW. The anti-inflammatory test showed activity with values of 41.12% (ethanol extract), 47.27% (ethyl acetate extract), and 54.09% (n-hexane extract). The antibacterial activity test provided different activities where the best activity was evident in ethanol extract to E. coli bacteria with inhibition zone size of 13.93 mm at a concentration of 1,000 ppm and ethyl acetate extract against S. aureus with an inhibition zone size of 13.03 mm at a concentration of 1,000 ppm. In the anticoagulant activity test, Lee-white's ethyl acetate extract had anticoagulant activity at a minimum concentration of 75 ppm and ethanol extract of itchy leaves at a minimum concentration of 30 ppm.
Keyword: Itchy leaves [Laportea decumana (Roxb.) Wedd.], Analgesic, Anti-inflammatory, Antibacterial, Anticoagulant
DOI: https://doi.org/10.31838/ijpr/2020.12.03.199
Download: Request For Article
 












ONLINE SUBMISSION
USER LOGIN


Username
Password
Login | Register
News & Events
SCImago Journal & Country Rank

Terms and Conditions
Disclaimer
Refund Policy
Instrucations for Subscribers
Privacy Policy

Copyrights Form

0.12
2018CiteScore
 
8th percentile
Powered by  Scopus
Google Scholar

hit counters free