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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Assessing the efficiency of Honeybee venom as an antimicrobial pathogenic agent

Author: ADNAN ABBAS, MUNTAHA A. AL-SAFAR, ZEYAD GATTEA AL-RIKABI, EMAN H. ABED
Abstract: Available antimicrobial agents are hard to use for various pathogenic microorganisms. At the same time, Honeybee venom has been widely applied as precious therapy for diverse inflammatory conditions and bacterial diseases. This toxin comprises in general vital syntheses, so, bee venom and melittin manifested similar levels of antimicrobial action. Different concentrations of bee venom (5, 15, 25, 50, 100, 150, 200, 250, and 300) µg/ml, was used as a determinant of the growth of pathogenic bacteria, like Staph. aureus and E. coli, and there are different affections on the density of cell dilution after cultivation for 120 min, at room temperature, with (1.881, 1.417, 0.962, 0.427, 0.414, 0.218, 0.158, 0.083, and 0.006) nm, and (1.395, 1.382, 1.452, 1.352, 0.801, 0.504, 0.462, 0.359, and 0.343) nm, respectively. Whereas, the same affected of bee venom concentrations were observed in measuring the biomass of Staph. aureus and E. coli, at the same condition, were (2.74, 2.22, 2.02, 1.86, 1.76, 1.58, 1.48, 1.16, and 1.1) mg/ml, and (0.7, 1.3, 2.1, 1.94, 1.4, 1.36, 1.22, 0.82, and 0.78) mg/ml, respectively.
Keyword: Honey bee venom, melittin, antibacterial activity, Staph. aureus, E. coli.
DOI: https://doi.org/10.31838/ijpr/2020.12.03.165
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