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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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A review of metabolic syndrome parameters: Key players in aging pathogenesis

Author: MOHAMMAD AFSHAR, SAMIRA ABBASZADEH-MASHKANI
Abstract: Metabolic syndrome represents a cluster of metabolic abnormalities (e.g., central obesity, hypertension, dyslipidemia, atherogenic, and insulin resistance), and is strongly linked to an enhanced risk for developing atherosclerotic, diabetes and nonatherosclerotic cardiovascular disease. To determine to what extent metabolic syndrome parameters are involved in the pathogenesis, and progression of aging. The scientific literature (Scopus, Google scholar, and PubMed) was searched from 1980 and 2020. The relationship among metabolic syndrome profiles and the aging is emerging as a public health question of importance to primary care practitioners. A number of studies have suggested a link between metabolic syndrome parameters with aging. Therefore, further investigations on the parameters of metabolic syndrome may be involved in the pathogenesis of aging. This review emphasizes the studies investigating the roles of metabolic syndrome, oxidative stress, inflammation, dyslipidemia, insulin resistance, overweight, high blood pressure, cardiovascular, type 2 diabetes in aging.
Keyword: Metabolic syndrome, Oxidative stress, Inflammation, Dyslipidemia, Insulin resistance, Overweight, High blood pressure, Cardiovascular, Type 2 diabetes, aging.
DOI: https://doi.org/10.31838/ijpr/2020.12.03.161
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