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Anti-hyperglycemic and Anti-hyperlipidemic effect of Rourea minor in streptozotocin (STZ) induced diabetic albino rats.
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| Author:
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UPLOADED BY-ADMIN, ANU CHAUDHARY, ANIL BHANDARI, A.PANDURANGAN
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| Abstract:
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Rourea minor (Gaertn.) Aubl. (Connaraceae), a woody vine (liana), is used extensively in the indigenous system of medicine
as an anti-diabetic agent. The current investigation focuses on the serum insulin augmentation and anti-hyperglycemic
property of methanolic extract of Rourea minor roots on streptozotocin induced diabetic rats. Type 2. diabetes was induced
by administering intraperitoneal injection of a Freshly prepared STZ solution (60 mg/Kg og body weight) in 0.1M cold
citrate buffer to the overnight fasted rats. The diabetes induced animals were fed with plant extract at the increasing dosage
of 100mg, 200mg and 400mg of body wt. The combined plant extracts administrated animals revealed a significant (P<0.05)
increment of serum insulin levels and higher reduction in hyperglycemia when compared to the diabetic control rats
(P<0.05).
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| Keyword:
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Rourea minor, streptozotocin (STZ), hyperglycemia, glucose tolerance test.
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| DOI:
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