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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Omadacycline extravasation: a general overview

Author: AISHWARYA MB, JERLIN ANUSHA, KHAYATI MOUDGIL
Abstract: Extravasation is an unintended release of intravenous fluids into the surrounding tissues, which may lead to inflammation, irritation and necrosis of the tissues. This happens primarily in intensive care patients due to a large number of regularly prescribed medications, multiple attempts and regular cancellations. Multiple puncture and vein gap holes and deterred venous structures should be avoided. If a lack of blood return from the cannula is generally referred to as a indication that extravasation has occurred. It is the most misleading of all symptoms and has been implicated in a variety of serious incidents. When using an infusion pump, close monitoring is required to test the flow rate, where potential changes in the location of the body, e.g. bending of the wrist or elbow, cannula support or bandaging, have been omitted as possible triggers, suggesting the risk of extravagance. Geriatrics and paediatrics are the primary casualties of extravagance. The understanding of how to treat these injuries differs depending on medications. Omadacycline is known to induce extravasation of the infusion site and has minimal treatment options. It is the first drug in the amino methylcycline antibiotic that belongs to the tetracycline subclass. Extravasation accidents remain rare, with a reported occurrence of between 0.1% and 6% recorded in the literature on inpatients receiving chemotherapy. Elimination of human error can be seen as training nurses and helping patients reduce the occurrence of extravasation and prevent local injuries. Infusion therapy therefore requires more medical care and understanding. It is important to know how to handle the complication.
Keyword: Extravasation, Tissue damage, Omadacycline, Infusion.
DOI: https://doi.org/10.31838/ijpr/2020.12.03.096
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0.12
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