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Article Detail
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Virulence Factors of Candida albicans Isolated from Vaginitis
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ENAS ALWAELI, RAHMAN LAIBI CHELAB, ENAAS SALEH JAWAD
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Candida albicans is colonizes in oral, gastrointestinal tract, skin, and vagina at many of anatomically distinct sites, a commensal C. albicans how harmless, It's not certain whether become a pathogen of human as opportunities come, This review will focus on the dissection of confirmatory diagnosis of C. albicans isolates by 18srRNA and study some Virulence factor genes that is importance and its effect on the female reproductive system, It also affects fetuses in pregnant women include With its impression share (INT1(31.42%), PlB1(100%), Hwp1(100%), SAP1(48.57%), SAP2(100%), ALS1(45,71%), CPH1(40%), CDR1(92.85%), MDR1(78.57%), from (300) female genital tract secretions specimens isolate ,The number of bacterial isolates was 165 (55%) and the number of yeast isolates was 110 (36,6%) and no growth 25(8,33%).The current study was isolated some types of yeast from women with vaginitis, belong to a genus Candida, C. albicans, C. krusei, C. tropicalis, C. glabrata , C. parapsilosisas, where the largest number and percentage was for C. albicans 70(63,6%),18 (16.3%),10(9.09%), 7 (6.36%), 5 (4.54%) Respectively, The results also showed that the resistance and sensitivity of the different types of antifungals (Nystatin, ketoconazole, Amphotericin B, Miconazole) used in the C. albicans fungus, The ratio of resistance (50 (71.4%), 42(60%), 37(52.8%), 30(42.8%) Respectively
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C. albicans, Virulence factor genes ,INT1, Hwp1, PlB1, SAP1,SAP2, ALS1, CPH1, CDR1, MDR1
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| DOI:
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https://doi.org/10.31838/ijpr/2020.12.02.189
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