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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Level of IgE and Leukotriene – B4 in Chronic Tonsillitis Bacterial Infection

Author: AWHAM DEHIOL, MAJIDA G. MAGTOOPH, RAID KAREEM DEHIOL AL-OKAILI
Abstract: This study aims to determine the levels of IgE and Leukotriene- B4 in chronic tonsillitis patients infected with S. pyogen and S. aureus that age ranges between 3-54 years in Thi-Qar province and their relationship with gender, age. This study included 75 patients with chronic tonsillitis infected with S. pyogen and S. aureus diagnosed with the use selective and differential media and biochemical tests, and diagnostic methods have also been used as API 20 and VITEK2 compact system, from both sex and with different ageat Al-Haboubi Teaching Hospital in Al-Nasiriya city, IgE levels were evaluated by Cobas® and Leukotriene- B4 by three generation ELISA system. The results shows the high prevalence bacteria was Streptococcus pyogen with 50.7%, and 26.7% of patients have a double infection of both , while Staphylococcus aureus were 22.6%. The results also showed that the highest incidence in the first age group and the lowest in the fourth age group, and in male higher than female. The level of IgE decreased in the patients infected with S. pyogen, the results also show there are non-significant difference between them at p. value ( = 0.05), while the Leukotriene- B4 level was not indicated when compared to the control group, only in the first age group there are significant differences at (p = 0.05).
Keyword: Leukotriene-B4, IgE, Tonsillitis, Pathogenic Bacteria
DOI: https://doi.org/10.31838/ijpr/2020.12.02.187
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