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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Metabolic Syndrome Parameters in Psychiatric Disease: Current knowledge and Future Perspectives

Author: SOMAYEH DEHKOHNEH, SARA AZADI, MORAD RASOULI-AZAD, JAFAR JALILIAN, AZAM GHASEMINEGHAD, NEDA VAHED, FARKHONDEH RAZZAGHI, LEILA JAFARI, SAMIRA ABBASZADEH-MASHKANI
Abstract: Psychiatric diseases are a significant source of disability worldwide. Psychiatric disorders like schizophrenia, anxiety, mood disorders, major depressive disorder, obsessive-compulsive disorder, attention deficit disorder with hyperactivity, autism spectrum disorder, tourette syndrome, bipolar disorder, anxiety disorder, sleep disorder, post-traumatic stress disorder, personality disorders, phobia, eating disorders, sexual disorder, and cognitive disorder affect a sizeable proportion of the human population and severely compromise quality of life. Thus, measures to prevent the manifestation, and treatments to ameliorate the signs, of these disturbance are in high demand. The relationship between severe psychiatric illnesses and the metabolic disturbances is emerging as a public health question of importance to both primary care practitioners and mental health. Although several evidence have demonstrated a link between oxidative stress, glycemic control, inflammation, and lipid profiles with psychiatric disorders. Another critical aspect that needs much attention and effort is our understanding of the association between metabolic syndrome parameters and severe psychiatric illnesses. This review includes relevant articles published between 1990 and 2019. The aim of this review article is to examines the current knowledge and future perspectives related to the role of metabolic disorder (e.g., oxidative stress, glycemic control, inflammation, and lipid profiles) in patients with psychiatric disorder.
Keyword: Oxidative stress, Glycemic control, Inflammation, Lipid profiles, psychiatric disease.
DOI: https://doi.org/10.31838/ijpr/2020.12.03.157
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0.12
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