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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Invitro Antioxidant Activity of Hydroalcoholic Extract of Crataegus Oxycantha Leaves

Author: ARUN KUMAR, VIPIN KUMAR GARG, DEVENDRA PATHAK
Abstract: Modern era is witnessing the human pathological conditions caused by reactive oxygen species apparently prevalent due to stressful way of life. Plants and herbs have been a great source of remedies to various human aliments. C. Oxyacantha is such a plant with richness of polyphenolic compounds useful in the treatment of various ailments. It has been used for so long as a pharmacologically active plant. Many parts of the plant have been extensively utilized to treat cardiovascular disorders angina, CHF, dysrhythmias and raised blood pressure. C. Oxyacantha is rich with hypatahydroxy flavan glycoside as well as flavan polymers. It also has oligomeric procyanidins and flavonoid constituents as the principle components of Crataegus oxycantha are responsible for its medicinal values. Being possessing various polyphenolic constituents like Quercetin, Hyperoside, Caffeic acid, Rutin, Vitamin C, the project got designed to investigate the antioxidant potential through invitro methods adopting Reducing power potential, Hydroxyl radical quenching, superoxide anion quenching activity and nitric oxide radical combating activity. The 70% hydroalcoholic extract of C. oxyacantha leaves has been emerged to exhibit significant antioxidant potential. The reactive oxygen species quenching potential may be attributed to flavonoids and other polyphenolic constituents preserved in the plant.
Keyword: C. oxyacantha, antioxidant activity, polyphenol compounds.
DOI: https://doi.org/10.31838/ijpr/2020.12.03.150
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