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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Transcription Analysis of Primary Genes Causing Endometrial Cancer from Cell Line Analysis

Author: B.J. NAIR, V. ROHITH
Abstract: Now a days endometrial cancer is most frequently occurring in women ,endometrial is the unusual growth in uterine wall which h lead to the cancer because of the primary mutation of the most frequently mutated gene PTEN.in our proposed work we have did the gene analysis of endometrial gene for expression analysis. Endometrial cancer is the most prevalent gynecological disease, but it is still rare enough for some genetic disease syndromes to have significance as a signature cancer. Commercial multigene research panels contain up to 10 specific genes annotated in women of endometrial cancer with the germline DNA study. Many other genes from guided genome-wide sequencing trials, or multigene panel study, or work have been identified as related to family endometrial cancer. This study assesses data to support relationship with endometrial cancer risk for 32 genes involved in inherited endometrial etrial people with cancer with projeccancer The Cancer Genome Atlas and provides a list of unusual germline features in these 32 genes found by the application of integrative proteiomic profiling of endometrial-based ovarian cancer cell lines
Keyword: PTEN, ICGC, PIK3CA.
DOI: https://doi.org/10.31838/ijpr/2020.12.03.110
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