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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Determine the efficacy of antibiotic prophylaxis and specific antibiotic regimens in dental implant placement for the prevention of postoperative infection (POI) in children: A Systematic Review and Meta-Analysis

Author: B KHOSRAVI, EHSAN GRAVAND, MARYAM SADEGHOLVAD, MAHROO MIRZA
Abstract: Background and aim: Conflicting proposals on antibiotic prophylaxis in dental implant placement reveal the require for investigation of current writing on the subject and re-evaluation of related dangers and benefits. So, the aim of this systematic review and meta-analysis was determine the efficacy of antibiotic prophylaxis and specific antibiotic regimens in dental implant placement for prevention of POI in children and adults. Method: MEDLINE, PubMed, Cochrane Library, Embase, ISI, google scholar were used as electronic databases to perform a systematic literature between 2015 to 2019. A commercially available software program (Endnote X9) was used for electronic title management. Searches were performed with keywords, “antibiotic”, “prophylaxis”,” antibiotic regimens”,” dental implant”, “implant” “post-operative infection OR POI ” , “children”, “pediatric dentistry”, “adults”,” healthy patients”. The present systematic review was performed based on the main consideration of PRISMA Statement–Preferred Reporting Items for Systematic Reviews and Meta-analysis Result: All antibiotic regimens group (RR 2.87, 95% CI 0.16 to 52.74), pre-operative only antibiotic group (RR 4.82, 95% CI 0.24 to 98.89), pre- and post-operative antibiotic group (RR 4.55, 95% CI 0.22 to 93.38). Conclusion: Antibiotic prophylaxis may not be shown for the anticipation of POIs following dental implant placement in generally healthy patients.
Keyword: antibiotic prophylaxis, antibiotic regimens, dental implant
DOI: https://doi.org/10.31838/ijpr/2020.12.03.092
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