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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Hypocalcaemia following total thyroidectomy without inferior thyroid artery ligation

Author: GHAITH NAYLA, ALI SAMEER AL SHAMMAA, LAYTH AL-SALIHI
Abstract: Background: Hypocalcaemia after total thyroidectomy is usually attributed to secondary hypoparathyroidism, which could be due the vascular compromise during dissection. Ligation of inferior thyroid artery (the main source of blood supply to the parathyroid glands) is a suspect for this compromise. The aim of study was determined hypoglycemia post thyroidectomy operation with no ligation of inferior thyroid artery. Methods: In Imamain Al-Kadhmian Medical City, after excluding preoperative hypocalcaemia, candidates for total thyroidectomy were operated without ligation of inferior thyroid artery and then were followed for six months looking for the incidence of postoperative hypocalcaemia at three intervals (day 3, month one, and month six). Results: Total number of enrolled patients was 201. Age varied from 22 to 62 years. Two-thirds of the sample aged between 30 and 49 years. Male to female ratio was 1:3.5. At postoperative day three, 65 patients were discovered having hypocalcaemia (prevalence 32.3%; 95%CI: 26.0%-39.3%) including three severe cases. After one postoperative month, 12 patients were still having hypocalcaemia (prevalence 6.0%; 95%CI: 3.3%-10.5%). After six post-operative months, two patients were still having hypocalcaemia (prevalence 1.0%; 95%CI: 0.2%-3.9%). No severe cases of hypocalcaemia were encountered again. No significant association was observed between developing early postoperative hypocalcaemia and any of age or sex of patients (P > 0.05). Conclusion: Avoiding inferior thyroid artery ligation during total thyroidectomy yielded postoperative hypocalcaemia in a comparable rate if ligation of this artery was done.
Keyword: Total thyroidectomy, hypocalcaemia, hypoparathyroidism, inferior thyroid artery, postoperative hypocalcaemia
DOI: https://doi.org/10.31838/ijpr/2020.12.03.068
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0.12
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