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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Study the relationship between NT-ProBNP and prolactin in sera of Iraqi patients with chronic renal failure

Author: BUSHRA HASSAN, SHAHAD FAWZI OBEID, NOUR SAEED HASSAN, SAMER ABDULHASAN MUHI
Abstract: chronic renal failure (CRF) is a disease that have impact of a multiple systematic organs in human body specially hearts, hormones, etc. The present study was carried out to appraise the possible correlation between N-terminal pro-brain natriuretic peptide (NT-ProBNP) and prolactin (PRL) levels in sera of Iraqi patients with chronic renal failure). The investigation populace included (90) subjects, among them (60) patients with chronic renal failure and (30) sound people that filled in as control gathering. NT-ProBNP was estimated by enzyme-linked immunosorbent assay (ELISA) while PRL hormone was measured by Immulite 1000 system, chemiluminescent immunometric assay. in this study we found a highly significant (P<0.01) increase in the levels of NT-ProBNP and prolactin in patients group compared with control group also we found a positive correlation between NT-ProBNP and prolactin hormone in patients group. This study concluded that there is a strong relationship between the NT-ProBNP and prolactin hormone, which was statistically significant correlations among them, as the levels of NT-ProBNP increased the levels of prolactin hormone increased in patients with chronic renal failure.
Keyword: NT-ProBNP, Prolactin, Chronic Renal Failure.
DOI: https://doi.org/10.31838/ijpr/2020.12.03.061
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