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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Potential antioxidant activity associated with methanol extract ofchrozophoratinctoria (L.) Rafin

Author: MUNA SAOUDI, MOHAMMED A. AUDA, NASSER GHALYYOUSIF
Abstract: The antioxidant activity of photochemical derived from plants play a role in cancer prevention, formation and treatment.The metabolicextractorChrozophoratinctoria (L) Rafin was examined to determine the varieties of photochemical, nutritional value, andestimated the phenolic compounds content. The respective extracts of its leaves, stems and roots were prepared by soxhlet extraction technique in methanol. The results confirmed the presence of flavonoids, polyphones and tannins as the most importantphotochemical. The percentage composition of various nutrition parameters (moisture, total ash, crude fat, protein, crude fiber, and carbohydrate) is showed that leaves had the highest moisture, ash contents, protein, fats, fiber, carbohydrate and gross energy than other parts. From the results achieved, phenolic compounds content determined used folin reagent method showed the presence of polyphones,tannins, and flavonoids. The total phenolic and flavonoid contents of methanol extract of the three parts (leaves, stems and roots) aredetermined as 38.15 mg of (GAE/gm), 25.07 mg of (GAE/gm) and 17.61 mg of (GAE/gm) respectively. In DPPH free radical scavenging test for antioxidant activity, the IC50 values (IC50 varied from 17.2 mg/mL in leaves, 22.2 mg/mL in stems to 24.7 mg/mL in roots). Hence, chrozophoratinctoria (L) Rafin mayhave medicinal properties against diseases.
Keyword: Chrozophoratinctoria, Methanol extract, Proximate Nutritional Analysis, Polyphones, Antioxidant.
DOI: https://doi.org/10.31838/ijpr/2020.12.02.0172
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