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Effect of Obesity,FSH, LH, Prolactin and Testosterone hormones levelsoninfertile patients
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| Author:
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MAMDOOH AL-NASRAWI, DR. SAMID A. RAMADAN , ZAHRAA N. ABBAS
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| Abstract:
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Many families are suffering from infertility that requires shedding light on the role of many factors participating
in this condition. Seminal fluid analysis results in the minimum overlap range with high sensitivity (78%) and
specificity (92%). The area under curve showed higher motility (90%) and concentration (84%) in comparison
with the morphology (70%) for WHO. Determination of hormone levels among the studied groups sera
showed that LH level was highly significantly elevated (34.699± 12.947) Pg/ mlin the patient's sera in
comparison with the control group (14.859± 10.487) Pg/ ml (P= 0.001).The LH level of =28. 5 IU/ml was highly
significant and may be used for the differentiation between infertile and healthy fertile males with a sensitivity
of 92.5%, specificity of 80.8% and accuracy of 90.1% (P=0.001). The level of LH may play a crucial role in
obesity of patients whereas it has impact on semen quality and subsequently male infertility.AG to A transition
was identified innt 4580 atND2 region. SNP is a synonymous substitution happening in the 3
methionine
codon position, leading to the change of the ATG codon to ATA codon.
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| Keyword:
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Obesity, FSH, LH, Prolactin, Testosterone, hormones, infertilepatients
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2020.12.02.0164
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| Download:
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