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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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The value of iron supplementation to children with Helicobacter pylori infection in Iraq: a cross-sectional study

Author: ASAAD ALZAIDY, ALI ALZAIDY, ISRAA NADHIM ABDULSATTAR
Abstract: A number of reports have linked iron deficiency anemia to H. pylori infection. This microorganism is extremely common worldwide and it is estimated to affect 50 % of population with some variations in the prevalence rates attributed to geographic, sociodemographic and other factors; nevertheless, it appears to be more common in developing countries in comparison with developed countries. In developing countries, H. pylori is estimated to affect approximately 65 % of children.The aim of the current study was to shed light on the possible association between H. pylori infection and iron deficiency anemia in children in our Iraqi community.The current study included 34 children who were recruited from the pool of children visiting the consultation unit of pediatric in Maternity and Children Teaching hospital in Al-Diwaniyah Province, Iraq. Some of patients were also recruited from a number of private clinics. Those children were serologically diagnosed to have H. pylori infection. Complete blood count was carried out in addition to assessment of serum ferritin. The beginning of the study is dated back to December the 2 2019.The mean hemoglobin (Hb) concentration was 9.64 ±1.02 g/dl and it ranged from 7.1 -10.9 g/dl; the frequency of anemic patients was 100.0 % based on the results of Hb in comparison with reference values. Besides, the mean mean corpuscular volume (MCV) was 71.94 ±7.82 fl and it ranged from 53.6 -84.5 fl; the frequency of patients with microcytic red blood cells (RBC), MCV < 77 fl, was 67.6 %. In addition, the mean mean corpuscular hemoglobin (MCH) was 20.97 ±3.01 pg and it ranged from 13.6 -27.1 pg; the frequency of patients with hypochromic RBCs, MCH < 25 pg, was 91.2 %. Moreover, the mean mean corpuscular hemoglobin concentration (MCHC) was 229.13 ±1.49 g/dl and it ranged from 25.4 -32.6 g/dl; the frequency of patients with hypochromic RBCs, MCHC < 31 g/dl, was 88.2 %. The mean serum ferritin of contributing children was 28.05 ± 18.05 ng/ml and it ranged from 8.6 -71.5 ng/ml; none of participating children had a serum ferritin level of < 7. children with iron deficiency anemia should be investigated for H. pylori even in the albescence of significant gastrointestinal manifestation because of the apparent association nd 2018 and ended on November the 15 th between this microorganism and iron deficiency anemia.
Keyword: iron supplementation;Helicobacter pylori; serum ferritin
DOI: https://doi.org/10.31838/ijpr/2020.12.02.0175
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