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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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In-Vitro Antibacterial Activity of Ethanolic Seed Extract of Aesculus Hippocastanum Against E. Faecalis

Author: UPLOADED BY-ADMIN, LAKSHMI. T, RAVISHANKAR. P
Abstract: Root canal failure that is caused during endodontic treatment is primarily by Enterococcus faecalis an facultative anaerobe . Herbal medicines that represent a rich source of antimicrobial agents are found to be effective against E.faecali. The aim of our study is to investigate the antibacterial activity of Aesculus hippocastanum(Horse chest nut) Ethanolic seed extract against Enterococcus faecalis, an facultative anaerobe that causes root canal failure in endodontic treatment. Antibacterial screening was performed by determining Minimum Bactericidal Concentration by broth culture method. The study concluded that the ethanolic seed extract of Aesculus hippocastanum does not show antibacterial activity at various concentrations ranging from 62µg/ml to 10mg/ml against E.Faecalis.
Keyword: Aesculus hippocastanum ,Anti-bacterial activity, MBC, Enterococcus faecalis.
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