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A Simple ElectroAnlytical Method for Estimation of Ofloxacin and Ornidazole Individually From Pharmaceutical Formulation
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| Author:
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UPLOADED BY-ADMIN, REGE P V, SATHE P A, SALVI V S
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| Abstract:
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In present study, a successful attempt has been made to develop a simple method for the determination of Ofloxacin and
Ornidazole individually using Differential Pulse Polarography technique. Quantification of Ofloxacin and Ornidazole was
done in Britton-Robinson Buffer pH 6.0 and pH 7.0 respectively using 0.1M KCl as a supporting electrolyte. Both Ofloxacin
and Ornidazole exhibit reduction cathodic peak in given respective pH with peak potential (Ep) as -1.28V for Ofloxacin and
-0.36V for ornidazole vs. S.C.E. 0.1N HCl was used as Solvent for the analysis. The parameters were used for method validation
are linearity; accuracy, precision, robustness, ruggedness, LOD and LOQ. Proposed method was found to be simple,
precise, and accurate and can be successfully applied for routine quality control analysis and determination Ofloxacin and
ornidazole individually in drug formulation.
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| Keyword:
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Differential Pulse Polarography (DPP), Ofloxacin, Ornidazole, Britton-Robinson Buffer.
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| EOI:
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| DOI:
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