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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Local Immunity of the Mouth in Patients with Chronic Kidney Failure Have or Have not Gemodialysis Treatment

Author: AVZAL AKBAROV, KOMOLA SHOAKHMEDOVA, SOBIROV MAKSUD ATABAYEVICH, SHAVKAT ALIYEV
Abstract: Objective: Evaluation of local oral immunity in patients with chronic renal failure receiving and not receiving hemodialysis therapy. Materials and Methods: This study was conducted in 108 patients. The formation of secretory immunoglobulin in saliva was determined using the Vector Best kits (Russia). The data obtained were processed using the program "STATISTICS-6.0". Calculated mean arithmetic values (M) and standard deviations (m). Reliability factors were calculated using Student's t-test. Results: The studies of saliva of patients with chronic renal failure receiving hemodialysis also showed a deficiency of lysozyme and sIgA. These indicators were significantly 1.4 times lower (P <0.001) than in the healthy control group, and 1.7 times lower than in patients with chronic renal failure who did not receive dialysis. It was found that PN in this group of patients was 46% and 53.3% higher than in the comparison group. Conclusions: These features should be taken into account in the treatment of diseases of the oral cavity in patients with chronic renal failure, especially in the case of prosthetics.
Keyword: chronic renal failure, hemodialysis, local immune status, phagocytic activity of neutrophils.
DOI: https://doi.org/10.31838/ijpr/2020.12.02.0108
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0.12
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8th percentile
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