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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Diagnosis of Alzheimer's Disease Using Principal Component Analysis and Support Vector Machine

Author: D.STALIN DAVID,
Abstract: The purpose of this study was the too early identification of Alzheimer's (AD) permits people and their health manages for medication. We have a tendency to plan an approach for classification of stages in AD and MCI, with regard to Texture with component analysis (PCA) based rule using magnetic resonance imaging (MRI) to detection of tissues in Alzheimer's Diseases. In the AD a hippocampus plays a most important affected region in the screening stage. Methods: The clinical Magnetic resonance images of brain tissue from the ADNI database having 180 AD patients, 401 MCI patients, and 200 control subjects are compared them with private OASIS dataset. The image can be stored in, jpg, bmp format and having an image size of 256x256 with the help of segmentation and SVM classification method. For testing and performance 20 brains MRI images were used Results: For the ADNI dataset accuracy rates of up to 94% and for the OASIS brain of up to 90% were obtained. The 91% accuracy of ADNI data is discriminated the OASIS of SVM classifiers Conclusions: The ADNI database with PCA feature extraction is the best dataset for to classify a MRI AD Images with help of SVM
Keyword: Computer Aided Diagnosis system, Alzheimer Disease, PCA, Support Vector Machine, ADNI database.
DOI: https://doi.org/10.31838/ijpr/2020.12.02.0106
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0.12
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