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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Clinical study of lower respiratory tract infections (LRTI) in pediatrics attending a tertiary care teaching hospital

Author: , SUSHANTA KUMAR DAS, MS. K. SOWMYA REDDY, MS. SYEDA SARVATH TAMKEEN, MR. DEBABRATA CHAUDHARY, MS. SMERA ELSA MATHEW
Abstract: Introduction: Lower respiratory tract infections (LRTIs) are one of the leading causes of morbidity and mortality among pediatrics in the developing countries like India. It is estimated that about 6,30,000 pediatrics die due to LRTI in India every year. Objective: present study was undertaken with the objectives to assess the vulnerable individuals, management strategy and to know the treatment outcome of various LRTIs with an aim to assess various clinical aspects of LRTI in pediatric patients admitted at a tertiary care teaching hospital. Methodology: case based prospective observational study was conducted for a period of 8 months during August 2018 March 2019 after obtaining permission from Institutional Ethical Committee, CMR College of Pharmacy, Hyderabad. Data were collected & analyzed according to inclusion and exclusion criteria. Discussion: a total 116 cases were included & analyzed for the study. Study outcome shows that, frequent age group was below 1year with male predominance. Cough and fever were mostly presented clinical feature whereas shortness of breath (SOB) and crepitation was with moderate appearance. Bronchopneumonia was the major occurred LRTI (65%) followed by bronchiolitis. Streptococcus pneumonia and Staphylococcus aureus was the frequent organism isolated. Amoxicillin with clavulanic acid was found to be drug of choice. Other antibiotics were minimal in prescription. Conclusion: present study concludes that children below 1 year of age are greatly vulnerable to LRTI, amoxicillin was the drug of choice and LOS was found to be 5-10 days. Treatment outcome was satisfactory as the mortality was found to be nil, with very negligible morbidity. Clinical Pharmacists counseling to new mothers for LRTI prevention in small children was an added benefit.
Keyword: LRTI, pediatrics, bronchopneumonia, amoxicillin.
DOI: https://doi.org/10.31838/ijpr/2020.12.02.0060
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