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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence

IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Article Detail

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Improved synthesis of antipsychotic drug – Quetiapine

Author: KOMPELLI SARAT, K. TATENDRA REDDY, P.S.R.CH.SHEKARROY
Abstract: The present communication reports the improved synthesis of an API molecule Quetiapine established by using R software for quality by design which improved the yield. An optimized synthesis by screening different solvents and bases was proposed. Finally better conditions for preparation of quetiapine were established using Quality by design.
Keyword: 11-chloro-dibenzo[b,f][1,4]thiazepine, 11-(piperazin-1-yl)dibenzo[b,f][1,4] thiazepine, 2-(2-chloroethoxy)ethanol
DOI: https://doi.org/10.31838/ijpr/2020.12.02.0053
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0.12
2018CiteScore
 
8th percentile
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