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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Detection Serum Antibodies for TORCH Infections during Aborted Pregnant Women in Fallujah, Iraq

Author: ASIF ABDULRAZAQ, HADEEL MOHAMMED FAYYADH, LAITH M. NAJEEB, KARWAN KHALID KADHAOM
Abstract: Background: Recurrent abortion may occur due to transmission of infections from uterus of the dam at several periods of pregnancy which may be produced by an extensive groups of pathogens which comprise of TORCH complex. Objectives: the aim of this study was to evaluate some serological tests during the acute TORCH infections in pregnant women in Fallujah city. Materials and Methods: A prospective study was done at the university of Fallujah collage of science from January 2019 till July 2019. This study involve (44 women) diagnosed with abortion. The age range from 18 to 45 years. All patients underwent blood tests in order to diagnose and characterize the infection by humane herpes virus 1 and 2, cytomegalovirus, rubella virus and blood parasite toxoplasma. The sera of all patients were analyzed for IgG antibodies to viruses and parasite included in this study using ELISA kit (Biomeriuex company - Spain) same company produced ELISA kit for IgM used in this research. Statistical analysis of the data was done by using SPSS-22 software. Results: The positive result of the current study showed that the IgG, IgM of pregnant women to toxoplasmosis is 43.2 %, 6.8% respectively. The results showed for a positive percentage of cytomegalovirus IgG, IgM (75; 9.1), and negative results (25, 90.9) respectively. Also, the results showed for a positive percent of Rubella virus IgG, IgM (63.6, 2.3) and negative results (36.4, 97.7) respectively, while the positive percent for herpes virus showed 11.4, 4.5 respectively. Conclusion: These TORCH Infections are widely present in our community and may be a real cause of abortion or congenital infection.
Keyword: TORCH, IgG, IgM, pregnancy, Fallujah.
DOI: https://doi.org/10.31838/ijpr/2020.12.01.201
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