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Microwave Synthesis, Characterization of Some Novel Curcumin Compound and its Metal Complexes with Antimicrobial, Antioxidant Studies
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| Author:
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ATHRA G.SAGER, AHMED A. SAHEEB, ATHRAA H. MEKKY
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| Abstract:
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The Schiff bases (L2-L4) have been synthesized through the condensing curcumin with 4-aminoantipyrine [L2], curcumino-4-aminoantipyrine and tyrosine [L3] in ethanol, and the condensing (1mol) of curcumino with (2mol) of 4-aminoantipyrine [L4]. The complexes of curcumin derivatives L1, L2, L3 and L4 with metal ions such as Cobalt (II), Ni (II) and Copper (II) have been manufactured. Altogether were categorized via the FT-IR, 1H-NMRand CHN analysis. For in-vitro antimicrobial test activities, the Schiff -bases as well as its complexes were used that provided a well consequences to the attendance of the metalsions than the ligand free when tested against a various of bacteria such as Escherichia coli, S. aureus as well as Salmonella typhi. Furthermore, the ligands and its complexes antioxidant activities also examined throughout their effects of scavenging by 2, 2-diphenyl-1-picrylhydrazyl [DPPH].
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| Keyword:
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Curcumino-di (4-aminoantipyrine), Metal Complex, Antimicrobial, Antioxidant.
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2020.12.01.200
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| Download:
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