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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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A Review on Sarcoidin Donkey

Author: MOHAMMAD KAREEM, RAFID KHALID ALI, INAM B. FALEH, MUSTAFA SALAH HASAN
Abstract: Equine sarcoids can be considered as the most common of the equine skin tumor types distributed worldwide which affects horses, donkeys and mules. The methods of transmission are environment contamination with successive trauma; skin infection direct or indirect transmissions from the affected animals; biting, rubbing, fomites or management practices and face flies. Dermatophytis, chronic skin rubbing, equine papilomatosis, squamous cell carcinoma, fibroma, fibrosarcoma, melanoma and granulation tissue are the common differential diagnoses of equine sarcoids. Bovine papillomavirus (BPV) is usually related to the equine sarcoids with the genetic, skin trauma and fly vectors that are characterized as possible factors of predisposing for disease development. Clinical examination, histopathology, detection of BPVDNA by PCR, electron microscope and immunohistochemistry are the diagnostic technique of equine sarcoid. The histopathological characteristics of sarcoids, have discovered that the classic epithelial variations in the hyperplasia, hyper-keratosis, picket fence, and elongated rete pegs. Treating equine sarcoids are difficult for veterinarians as a result of variable clinical presentation of lesions and frequent local recurrence cases. Each of the surgical and the non-surgical approaches are utilized to treat equine sarcoids with variable success rates. No existing approach ofequine sarcoids’ treatment has proven 100% efficient. Awareness enhancement to make equine owners, prevention offly contact,use of breeding from those individuals thatare‘immune’,high geneti cresistance, early diagnosis and treatment of any confirmed lesions are the most valuable prevention methods for equine sarcoids.
Keyword: Sarcoidin, factors, recurrence, hyperplasia, hyper-keratosis, picket fence
DOI: https://doi.org/10.31838/ijpr/2020.12.01.190
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