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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Replacement of Gelatin in capsules shell manufacturing - A Review

Author: ARAVINDHANATHAN VENKATESAN, ARUN RADHAKRISHNAN, KATTAMURI SAHITHI, GOWTHAMARAJAN KUPPUSWAMY
Abstract: Capsules are the unit solid dosage forms in which the drug can be incorporated into the shell. Gelatin is the major polymer used for capsule preparation which is natural polymer obtained from animal source i.e. skin and bones of pigs and cows. The usage of gelatin in capsule making is decreased due to many reasons like source of gelatin is from animals which causes mad cow disease and cross linking of gelatin with drugs which decreases the efficiency of drug. Because of this reason, development of capsule shell using various raw materials is necessary to replace the gelatin. Moreover this review helps the capsule manufacturer to prepare the capsule shell using other synthetic and natural polymer.
Keyword: Capsules, Hard capsules, Synthetic polymers, Natural polymers.
DOI: https://doi.org/10.31838/ijpr/2020.12.02.0045
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0.12
2018CiteScore
 
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