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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Synthesis and Characterization of 1,4-Dihydropyridine Derivatives

Author: L. NASSIR,, M. S. MAGTOOF
Abstract: The researchers in the current study have some of the corresponding synthesis and characterization successfully 1,4-dihydropyridin a (1-3) drivatives. The compounds were synthesized by reaction of an aromatic aldehyde,ethylacetoacetate and ammoniume acetate in the presence of ethanol and t-BuOKwith at 60-65OC. Spectroscopy “Spectral measurements” (for example: 13C-NMR, 1H-NMR and FT-IR) have been used to characterize the synthesized compound product obtained and study the structural chemistry.
Keyword: Synthesis, Characterization,1,4-dihydropyridine, Hantzsch reaction.
DOI: https://doi.org/10.31838/ijpr/2020.12.02.0041
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