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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Rationale for sublingual allergen-specific immunotherapy in immunocompromised patients

Author: FATIMA IRSALIEVA, ILMIRA RAZIKOVA, ZAYNITDIN KAMALOV, NAZIFA DUSTBABAYEVA, KUTBIDDIN NIZAMOV
Abstract: The dynamics of immunological status parameters was studied in 62 patients with persevering allergic rhinitis (PAR) who received a full course of allergen-specific immunotherapy (ASIT). Monitoring of immunological parameters level was carried out before immunocorrective therapy and after the ASIT course. The effectiveness of ASIT in patients with ATS is characterized by a high baseline immunological parameters CD3+; CD4+; CD8+ and IgG and changes in blood concentration IL-4, IL-6, IL-8 at the early stages of treatment.
Keyword: lymphocytes, immunocompetent cells, allergen-specific immunotherapy, persistent allergic rhinitis, cytokines, interleukines
DOI: https://doi.org/10.31838/ijpr/2020.12.02.0032
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