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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Effect of endothelial dysfunction on metabolic syndrome development

Author: RIKHSI SABIROVA, GULNORA KASIMOVA, KHURSHIDA YUSUPKHODJAEVA, DILZODA AZIZOVA
Abstract: Endothelial dysfunction in metabolic syndrome is a closely associated state and forms a vicious circle leading to metabolic and cardiovascular disorders. Inflammation activates the expression of pro-inflammatory mediators of inducible form of NO-synthesis, which leads to the synthesis of peroxynitrite in the body. In the dynamics of experimental metabolic syndrome expressed changes in endothelial dysfunction indicators are observed on the 60th day of experience.
Keyword: metabolic syndrome, endothelium, blood, cytokines, nitrogen oxide, homocysteine, Willebrand factor.
DOI: https://doi.org/10.31838/ijpr/2020.12.02.0030
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0.12
2018CiteScore
 
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