Specific activity of a new antiallergic ointment in the treatment of contact allergic dermatitis
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Author:
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KHAIRULLA KHATAMOV, SHUKHRAT ZIYADULLAEV, AKRAM SUYAROV, VADIM KIREEV, SHERZOD MUKHTOROV
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Abstract:
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In this paper, we studied the results of the effectiveness of the ointment isolated from a new thick extract of the sum of flavonoids from local raw materials on a hydrophobic basis in an experiment on Guinea pigs with allergic contact dermatitis caused by 2,4-dinitrochlorobenzene. The results of the study showed that 5 % ointment drug based on a thick extract of the sum of flavonoids, more effectively reduces the skin folds compared to 1%, 3% ointment based on a thick extract of the sum of flavonoids and antihistamine psilo-balsam and celestoderm's glucocorticosteroid ointment. When analyzing the measurement of local temperature, the temperature in the 4-group of animals began to approach the initial level earlier than in other groups of experimental animals.
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Keyword:
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atopic dermatitis, sums of flavonoids, Bidens tripartita, ointment, contact allergic dermatitis.
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EOI:
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DOI:
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https://doi.org/10.31838/ijpr/2020.12.02.0029
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