IJPR  articles are Indexed in SCOPUSClick Here     Impact Factor for Five Years is 0.13 (2013 - 2018).    

logo

INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence

IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
Current Issue
Article In Press
No Data found.
ADOBE READER

(Require Adobe Acrobat Reader to open, If you don't have Adobe Acrobat Reader)

Index Page 1
Click here to Download
IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

Click to download
 

Article Detail

Label
Label
Antioxidant Activities and Identification of Compounds in Ethyl Acetate Fraction, Dichloromethane Fraction And Ethanol Extract Of Garcinia mangostana L. Leaves

Author: DINIATIK , ANIS KUSUMAWATI, AGUS SISWANTO, DIANA MARTALIA DOTI
Abstract: Mangosteen leaves (Garcinia mangostana L.) are a good source of antioxidants. The compounds contained therein are flavonoids and xanthone. This study aims to compare antioxidant activity and identify active compounds and to determine the types of flavonoids from ethanol extract, dichloromethane fraction and ethyl acetate fraction of G. mangostana leaves. The maceration method was used as extraction with solvent 70% ethanol. The thick extract was hydrolyzed using 2 N hydrochloric acid, then partitioned with dichloromethane and ethyl acetate. Ethanol extract, dichloromethane fraction, and ethyl acetate fraction were tested for antioxidant activity using DPPH method with UV-Vis spectrophotometer and quercetin as standard. The IC50 value of ethanol extract, dichloromethane fractions and ethyl acetate fraction were 0.819 µg/mL, 0.723 µg/mL, 0.025 µg/mL. Flavonol Quercetin as a standard has IC 50 of 0.131 µg/mL. It indicates that the extract and fraction of G. mangostana leaves have potent antioxidant activity and ethyl acetate fraction has higher antioxidant activity than other solvents.
Keyword: Garcinia mangostana L, antioxidant activity, ethyl acetate fraction, ethanol extract
DOI: https://doi.org/10.31838/ijpr/2020.12.02.0010
Download: Request For Article
 












ONLINE SUBMISSION
USER LOGIN


Username
Password
Login | Register
News & Events

Terms and Conditions
Disclaimer
Refund Policy
Instrucations for Subscribers
Privacy Policy

Copyrights Form

0.12
2018CiteScore
 
8th percentile
Powered by  Scopus
Google Scholar

hit counters free